David Thaisrivongs: Goldilocks and the First Oral PCSK9 Inhibitor

David Thaisrivongs: Goldilocks and the First Oral PCSK9 Inhibitor

Every so often, a technology quietly (and seemingly suddenly) crosses the line from an intriguing scientific idea into a paradigm capable of changing an entire industry. That’s precisely what’s happening with biocatalysis: the use of natural or engineered biological systems—specifically enzymes or whole living cells—to accelerate and direct chemical transformations. For decades, researchers dreamed of harnessing engineered enzymes to manufacture…