TAU researchers use gene editing to shrink tumors

TAU researchers use gene editing to shrink tumors

'In this study, we demonstrated that there are in fact some genes without which a cancer cell cannot survive, making them excellent targets for CRISPR therapy,' said Prof. Dan Peer.

CRISPR Breakthrough: Israeli Researchers Eradicate Tumors by Targeting a Single Gene

Head and neck cancers rank fifth in cancer-related mortality and often begin in the tongue, throat, or neck before metastasizing.

CRISPR Therapy Eliminates 50% of Head and Neck Tumors in Preclinical Study

Researchers at Tel Aviv University have demonstrated that CRISPR gene editing can effectively eliminate head and neck tumors by directly injecting lipid nanoparticles (LNPs) carrying CRISPR components into tumors. In a study published in Advanced Science, they reported that 50% of treated tumors disappeared after 84 days, marking a significant advance in precision cancer therapy. Gene editing to collapse cancer cells Head and neck squamous cell …

The gene or genetic edition CRISPR, acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a technique of genetic engineering in molecular biology that allows to modify the genomes of living organisms, through a simplified version of the bacterial antiviral defense system CRISPR-Cas.9 Recently, a group of researchers from the University of Tel Aviv led by Dr. Razan Masarwy and the team of Professor Dan Peer, achieved an unprec…

CRISPR Therapy Eliminates 50% of Head and Neck Tumors

Researchers used CRISPR to cut the SOX2 gene in head and neck tumors, eliminating 50% of cancers in mice and paving the way for new cancer therapies.