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Protein Restriction May Promote Healthy Aging and Longevity

The review of more than 350 studies says lower protein may improve metabolism and activate FGF21, a hormone linked to longer lifespan in animals.

  • On Friday, a review of more than 350 studies published in Cell Press Blue suggested that reducing protein intake may slow aging and improve metabolic health, particularly for sedentary adults.
  • Current U.S. dietary guidelines, updated this year by Secretary of Health Robert F. Kennedy Jr., recommend 1.2 to 1.6 grams of protein per kilogram of body weight, nearly doubling the previous target of 0.8 grams.
  • The hormone FGF21, which rises when protein intake is low, helps convert white fat cells into energy-burning beige fat cells, improving blood sugar control and reducing inflammation according to researchers.
  • Active individuals may be protected from high protein's downsides because exercise directs amino acids into muscle growth, University of Wisconsin-Madison biologist Dudley Lamming notes, suggesting recommendations should be personalized by activity level.
  • Nutritionist Joseph Matthews of the University of Arkansas for Medical Sciences emphasizes that "what we need is a handful of high-quality human studies," noting that translating animal findings to humans remains debatable.
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19 Articles

Lean Left

A groundbreaking warning has come from the international scientific community against the global trend of protein-enhanced foods. Researchers who examined more than 350 academic studies revealed that high protein consumption accelerates aging in sedentary individuals, and reducing intake could extend lifespan.

·Istanbul, Türkiye
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Lean Right

Protein shakes with whey have become popular in recent years. Pexels Bars, drinks and protein coffees are increasingly common on supermarket shelves as options sold as healthy to give satiety. But a review of more than 350 scientific studies suggests that, for a considerable portion of the population, the secret is precisely the opposite: consume fewer proteins. .This is what pointed out a survey published in the scientific journal "Cell Press B…

·Rio de Janeiro, Brazil
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Scientific American broke the news on Friday, July 31, 2026.
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