Computational framework sheds light on how the brain's decision-making is impacted in psychiatric disorders

Computational framework sheds light on how the brain's decision-making is impacted in psychiatric disorders

Scientists from the Icahn School of Medicine at Mount Sinai, working in collaboration with a team from the University of Texas at El Paso, have developed a novel computational framework for understanding how a region of the brain known as the striatum is involved in the everyday decisions we make and, importantly, how it might factor into impaired decision-making by individuals with psychiatric disorders like post-traumatic stress disorder and s…

Brain Circuit Model Reveals How Striatum Shapes Everyday Decisions

Researchers have developed a computational framework that maps how the striosomal compartment of the striatum governs everyday decision-making. By integrating biology, decision theory, and mathematical modeling, the study reveals that different levels of striosomal activity can push individuals toward impulsive, balanced, or overly complex decisions.