Scientists Discover a Simple Set of Rules That May Explain How Our Tissues Stay Organized

Researchers at ChristianaCare and UD uncover possible “Tissue Code” behind how human bodies stay organized

Gary Schleiniger, Ph.D., and Bruce Boman, M.D., Ph.D., longtime collaborators behind the study, uncovered potential rules of tissue organization. (Photo courtesy ChristianaCare) Researchers from ChristianaCare’s Helen F. Graham Cancer Center & Research Institute and the University of Delaware have uncovered what may be a fundamental set of rules that keep human tissue organized, even as the body replaces billions of cells every day. In a recent …

New study cracks the “tissue code” — just five rules shape organs

Scientists have uncovered a surprisingly simple “tissue code”: five rules that choreograph when, where, and how cells divide, move, and die, allowing organs like the colon to remain flawlessly organized even as they renew every few days. Mathematical models showed that manipulating just these parameters faithfully recreates real tissue architecture, hinting that the same code may govern skin, brain, and more. The discovery offers a fresh way to …

Scientists Discover a Simple Set of Rules That May Explain How Our Tissues Stay Organized

WILMINGTON, Del.--(BUSINESS WIRE)--Jul 15, 2025-

Computational biology unlocks rules of tissue self-organization

A team of researchers at ChristianaCare's Helen F. Graham Cancer Center & Research Institute and the University of Delaware believe they've found an answer.

New Study Identifies Five Core Principles Preserving Tissue Structure

The human body undergoes a daily replacement of billions of cells, but the tissues remain flawlessly organized. How can that be?

New study cracks the “tissue code” — just five rules shape organs - Conservative Angle

Scientists have uncovered a surprisingly simple “tissue code”: five rules that choreograph when, where, and how cells divide, move, and die, allowing organs like the colon to remain flawlessly organized even as they renew every few days. Mathematical models showed that manipulating just these parameters faithfully recreates real tissue architecture, hinting that the same code may govern skin, brain, and more. The discovery offers a fresh way to …