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New Research Identifies Critical Gene for Treatment

MIYAGI PREFECTURE, JAPAN, JUL 25 – Researchers found UNC13A disruption is a shared molecular mechanism in ALS caused by multiple RNA-binding protein defects, highlighting a key target for future therapies.

Summary by News Medical
Amyotrophic lateral sclerosis (ALS) - which you may know as the disease that affected Stephen Hawking - is a fatal neurodegenerative disease that causes progressive muscle weakness. A research team at Tohoku University and Keio University has uncovered a unifying mechanism in ALS revolving around the expression of UNC13A (a gene crucial for neuronal communication) that represents a common target for developing effective treatment strategies that…

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Medical Xpress broke the news in on Friday, July 25, 2025.
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