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Colorectal Cancer Outcomes Explained by Distinct Regulatory T-Cell Subsets
According to the American Cancer Society, colorectal cancer is the second leading cause of cancer death. Enrichment of regulatory T cells (T-regs) in solid cancers is generally associated with poor prognosis because these cells dampen the immune system’s ability to fight against a tumor. However, colorectal cancer stands out as an exception, as high density of T-regs in colorectal tumors is associated with improved survival. The mechanism for th…
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1 Articles
Colorectal Cancer Outcomes Explained by Distinct Regulatory T-Cell Subsets
According to the American Cancer Society, colorectal cancer is the second leading cause of cancer death. Enrichment of regulatory T cells (T-regs) in solid cancers is generally associated with poor prognosis because these cells dampen the immune system’s ability to fight against a tumor. However, colorectal cancer stands out as an exception, as high density of T-regs in colorectal tumors is associated with improved survival. The mechanism for th…
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