Cnio Discovers Link Between Fertility and Immune Cells in the Brain

Salud a Diario

Factuality

Ownership

An investigation by the National Center for Oncological Research (CNIO) with animal models has just found that two unsuspected elements are also involved in this hormonal regulation system: microglia, which are defensive cells of the nervous system, and RANK protein, which contributes to the remodeling of bones and is essential in the functioning of the mammary glands. The work is published online in Science magazine on March 12, 2026. It is dir…

upday

Factuality

Ownership

CNIO Discovers Brain Immune Cells Regulate Fertility (Symbolic Image - AI Generated) A team from the Spanish National Cancer Research Centre (CNIO) has discovered that immune cells in the brain directly regulate fertility. The finding, published this Thursday in the journal *Science*, reveals that microglia influence reproductive neurons through the RANK protein, challenging the traditional view that fertility depends exclusively on neural circu…

CNIO

Factuality

Ownership

The signal for puberty to begin begins in the brain. Specifically in the hypothalamus, where specific neurons release a hormone that activates the pituitary gland, at the base of the skull, which in turn releases other hormones that trigger the maturation of the gonads – the ovaries or the testicles. This mechanism, culminating in a fertile organism, is the hypothalamus-hypophysus-gonadal axis.

udgtv

Factuality

Ownership

Madrid, Spain. Researchers from the Spanish National Center for Oncological Research (CNIO) have discovered unexpectedly and in animal models a link between fertility and immune cells present in the brain and that would participate in the process of sexual maturation. CNIO discovers link between immune cells and fertility The research has been done in animal models, but the findings have also led to detecting mutations associated with a rare syn…