Ageing Is Linked to Inflammation — but only in the Industrialized World
- On June 30, researchers reported high inflammation levels in two indigenous groups that do not increase with age, linking inflammation to industrialised lifestyles, not ageing.
- Building on decades of ageing research, the study compared four populations—Italy, Singapore, the Tsimane, and Orang Asli—to assess how lifestyle influences inflammation beyond age-related effects.
- Analysis of blood samples from 2,876 adults across four populations shows 19 cytokines linked to inflammation, with ageing patterns only in industrialized groups, challenging universal inflammaging theory.
- The journal Nature Aging asserts that inflammaging is largely a byproduct of industrialised lifestyles, calling for holistic research on environment, culture, and lifestyle factors.
- Researchers call for larger, diverse longitudinal studies and the development of standardized, context-aware tools to better understand how environmental factors influence inflammaging.
17 Articles
17 Articles
Inflammation is increasing in this country in old age – and with them chronic diseases. But now a study shows that this is not the case everywhere.


New study suggests common assumption about aging could be wrong
‘It’s a warning – don’t follow the latest trends of eating foods specifically to reduce inflammation, or whatever else the trend of the week may be,’ said professor Alan Cohen
People living in industrialized countries have a link between age-related diseases and chronic inflammation. However, this link does not appear to hold true among some indigenous peoples, an international study suggests.
Aging-related inflammation is not universal across human populations, new study finds
Inflammation, long considered a hallmark of aging, may not be a universal human experience, according to a new study from Columbia University Mailman School of Public Health. The research suggests that "inflammaging"—chronic, low-grade inflammation associated with aging—appears to be a byproduct of industrialized lifestyles and varies significantly across global populations.
A new study shows that the same indicators of inflammation with age do not appear in non-industrialized populations, indicating the importance of lifestyles in ageing.
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