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Childhood maltreatment may alter sperm, affecting future generations' brain development

Summary by Medical Xpress
Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development.

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Early Stress Alters Sperm DNA, Impacting Offspring's Brain Development

Childhood stress may leave lasting marks on sperm, altering epigenetic profiles and potentially influencing brain development in offspring. Researchers found that men with high levels of childhood maltreatment had changes in DNA methylation and non-coding RNA levels in their sperm.

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Childhood maltreatment affects sperm epigenome and may impact brain development of next generation

Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development. This ground-breaking discovery has been made in the FinnBrain study at the University of Turku in collaboration with researchers from the University of Copenhagen in Denmark.

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Medical XpressMedical Xpress

Childhood maltreatment may alter sperm, affecting future generations' brain development

Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development.

Read Full Article
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Medical Xpress broke the news in on Wednesday, January 8, 2025.
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