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Chai Discovery Team Releases Chai-2: AI Model Achieves 16% Hit Rate in De Novo Antibody Design
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Chai Discovery Team Releases Chai-2: AI Model Achieves 16% Hit Rate in De Novo Antibody Design
TLDR: Chai Discovery Team introduces Chai-2, a multimodal AI model that enables zero-shot de novo antibody design. Achieving a 16% hit rate across 52 novel targets using ≤20 candidates per target, Chai-2 outperforms prior methods by over 100x and delivers validated binders in under two weeks—eliminating the need for large-scale screening. In a significant advancement for computational drug discovery, the Chai Discovery Team has introduced Chai-2…
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