Toronto Researchers Launch 5-Year Liquid Biopsy Trial for Cancer Survivors
The study will enroll more than 7,000 patients to test whether blood tests can confirm remission and detect cancer recurrence earlier.
- On Wednesday, researchers from the University Health Network in Toronto launched the five-year SHERLOCK clinical trial, enrolling more than 7,000 cancer survivors to test liquid biopsies for detecting disease recurrence.
- Liquid biopsies analyze blood samples for traces of tumour DNA, identifying microscopic cancer remnants that traditional scans miss after patients complete curative treatments.
- Funded by a $50-million donation from the Peter Gilgan Foundation, the study aims to determine if tests can spare survivors from unnecessary treatments or enable early intervention for those with residual disease.
- Paul Lonergan, a 68-year-old Toronto resident treated for throat cancer, received a liquid biopsy that detected tumour fragments, enabling immunotherapy and successful recovery monitoring.
- Dr. Ramy Saleh, a cancer researcher at McGill University Health Centre in Montreal, said the approach could "revolutionize" cancer monitoring, though clinicians stress these tests are not yet standard of care.
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Blood test to detect cancer recurrence being studied at Toronto’s Princess Margaret Cancer Centre
Researchers at Princess Margaret Cancer Centre in Toronto are working on a large trial to determine if a blood test can detect tiny amounts of cancer remaining after patients have been treated. Lead investigator Dr. Lillian Siu says smaller studies around the world have shown evidence that cancer DNA can show up in the blood in amounts too small to be identified by CT scans. But large-scale studies are needed to prove that so Siu and her team…
Toronto-based researchers are conducting a large clinical study to answer the question, and they have already managed to help one person.
Researchers at the Princess Margaret Cancer Centre in Toronto are currently conducting an extensive clinical trial to determine whether a blood test detects tiny amounts of residual cancer cells after treatment.
Can a blood test tell patients if their cancer is coming back? Researchers are working on it
Researchers at Princess Margaret Cancer Centre in Toronto are working on a large trial to determine if a blood test can detect tiny amounts of cancer remaining after patients have been treated.
The Toronto Star
Can a blood test tell patients if their cancer is coming back? Researchers are on it
TORONTO - Researchers at Princess Margaret Cancer Centre in Toronto are working on a large trial to determine if a blood test can detect tiny amounts of cancer remaining after
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