Building the Brain Requires Millions of Dangerous DNA Breaks
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2 Articles
Building the Brain Requires Millions of Dangerous DNA Breaks
Scientists discovered that building a healthy brain involves an unexpected step: young neurons routinely break and rapidly repair their own DNA. As the brain develops, newly formed nerve cells must travel through tightly packed tissue to reach the locations where they will become part of the brain’s neural networks. That demanding journey turns out to [...]
A recent study published in the journal Nature reveals that developing neurons break and repair their DNA during migration through the forming brain. The research, conducted by scientists at the Institute of Cellular and Integrated Materials Sciences at Kyoto University, highlights the importance of this process for healthy brain formation and the genetic uniqueness of neurons. DNA breakage and repair in developing neurons During migration, neur…
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