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What's Going On With Bristol Myers Squibb Stock Friday? - Bristol-Myers Squibb (NYSE:BMY)

Bristol Myers Squibb paid $1.5 billion to acquire Orbital Therapeutics and expand its cell therapy portfolio targeting autoimmune diseases with the experimental OTX-201 candidate.

  • On Oct 10, 2025, Bristol Myers Squibb announced in Bengaluru it will acquire privately-held Orbital Therapeutics for $1.5 billion in cash, pending regulatory review.
  • Seeking to broaden beyond blockbusters, BMS acquired Orbital's proprietary RNA platform and OTX-201, an in vivo CAR T candidate targeting autoimmune diseases.
  • Most of the $1.5 billion cash payment and milestone structure is payable at closing, with remaining payments tied to preclinical and early clinical milestones for OTX-201.
  • On Oct 10, BMY stock ticked up about 0.3%, suggesting investors had largely priced in or were cautiously optimistic about the company's first major acquisition this year beyond Eliquis and Revlimid.
  • Orbital aims to begin human trials of OTX-201 in early 2026, after which its collaboration with Beam Therapeutics will continue amid a ~$200B global autoimmune therapeutics market by 2031.
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Business Wire broke the news in Crystal River, United States on Thursday, October 9, 2025.
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