Brain Stimulation Reverses Synaptic Damage in Alzheimer’s

Brain Stimulation Reverses Synaptic Damage in Alzheimer’s

New research shows that low-intensity repetitive transcranial magnetic stimulation (rTMS) can restore key synaptic structures in mouse models of Alzheimer’s disease. The study found that axonal boutons—sites where neurons form connections—had reduced turnover in Alzheimer’s mice, indicating impaired brain plasticity. After a single rTMS session, the turnover of one bouton type significantly increased, matching levels seen in healthy mice.