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The Five ‘Ages’ of the Human Brain: Crucial Changes Occur Around the Ages of Nine, 32, 66 and 83

The study analyzed MRI scans of over 3,800 people to define brain network changes and key turning points linked to cognitive and neurological health, researchers said.

Summary by El Pais
The human brain is home to some 86 billion neurons. These are the “mysterious butterflies of the soul,” as Nobel laureate Santiago Ramón y Cajal called them, the principal cells of the nervous system, responsible for carrying all the information that allows us to think, laugh, remember, or breathe. These butterflies communicate, Cajal said, through “kisses,” the synapses, weaving sophisticated connections to transmit the nerve impulses that buil…

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The brain goes through five different phases in life, with key turning points at 9, 32, 66 and 83 years, says a group of scientists.

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Scans of thousands of people provide information on the development phases of neural architecture.

The fascination with the functioning of the human brain has guided studies that reveal, every day, more mysteries about how it ages over time. What was previously assumed as a simple progressive deterioration, is now described as a journey full of alternate changes, in which some processes even improve with the years. Knowing the five critical stages allows adapting expectations and strategies for both cognitive health and emotional well-being, …

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El Pais broke the news in Spain on Tuesday, November 25, 2025.
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