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Blood test identifies HPV-associated head and neck cancers up to 10 years before symptoms
The HPV-DeepSeek blood test detects HPV-linked head and neck cancers up to 10 years before symptoms, with 79% detection accuracy in patients who later developed cancer, researchers said.
- Recently, Mass General Brigham's HPV-DeepSeek blood test detected HPV-associated head and neck cancers years before symptoms, a study published in the Journal of the National Cancer Institute found.
- Researchers warn rates of HPV-associated head and neck cancers rise annually, and earlier diagnosis could increase treatment success and reduce aggressive therapies, authors say.
- Using ARIC samples from 16,000 U.S. participants, liquid biopsy assays detected circulating tumour DNA in early samples despite signals up to 50 times weaker years before diagnosis.
- In India, experts say the test could enable earlier treatment and risk stratification for tobacco users and the elderly, but deployment faces validation, regulatory approval, cost, and screening programme challenges.
- This breakthrough marks the start of proactive oncology, where a routine blood test could flag cancer early and experts say screening in high-risk countries could arrive within a decade.
11 Articles
11 Articles
This new blood test can catch cancer 10 years early
Scientists at Mass General Brigham have created HPV-DeepSeek, a blood test that can detect HPV-linked head and neck cancers nearly a decade before diagnosis. By finding viral DNA in the bloodstream, the test achieved 99% sensitivity and specificity. This breakthrough could lead to earlier, less invasive treatments and significantly improve survival. A large NIH trial is underway to confirm the results.
Cancer blood test: breakthrough that detects disease years before symptoms, when will India get it?
Scientists have developed a blood test that can detect head and neck cancer years before symptoms appear, according to a study in the Journal of the National Cancer Institute. Experts say it could transform early diagnosis in India, where late detection remains a major challenge.
Breakthrough Blood Test Detects Head and Neck Cancer up to 10 Years Before Symptoms
Mass General Brigham’s HPV-DeepSeek test enables much earlier cancer detection through a blood sample, creating a new opportunity for screening HPV-related head and neck cancers. Human papillomavirus (HPV) is responsible for about 70% of head and neck cancers in the United States, making it the most common type of cancer linked to the virus. Rates [...]
Test detects HPV-associated head, neck cancer 10 years early — Harvard Gazette
Daniel Faden in his lab at Mass Eye and Ear. Mass Eye and Ear Health New blood test detects HPV-associated head and neck cancer 10 years early Tool identifies disease before symptoms appear Mass General Brigham Communications September 10, 2025 3 min read Human papillomavirus (HPV) causes an estimated 70 percent of head and neck cancers in the U.S., making it the most common cancer caused by the …
New blood test exhibits superior sensitivity in detecting HPV-associated head and neck cancers: Study
A new liquid biopsy blood test could help detect cases of human papillomavirus (HPV)-associated head and neck cancers with significantly higher accuracy than currently used methods, including before...
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