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Guardians Host the Orioles to Begin 4-Game Series
CUYAHOGA COUNTY, OHIO, JUL 21 – The Guardians hold a series lead as both teams, under .500, fight for playoff chances with Cleveland winning eight of their last 10 games, records show.
- The Cleveland Guardians hosted the Baltimore Orioles on Monday, July 21, 2025, at Progressive Field to start a four-game series.
- Both teams entered the series with losing records, Cleveland at 49-50 and Baltimore at 44-55, while key players on both rosters were sidelined with injuries.
- Guardians pitcher Tanner Bibee started against Orioles pitcher Tomoyuki Sugano , with Cleveland holding an 8-2 record when scoring five or more runs.
- The season series was tied 2-2, with Cleveland favored at-142 on the money line, an over/under of 8.5 runs, and projections estimating a close 5-4 Guardians win.
- Both teams need to sweep the series to improve their Wild Card chances, making each game critical for postseason hopes.
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24 Articles
Marietta Daily Journal
WTVBOrioles to start RHP Zach Eflin on Wed.; C Adley Rutschman near return
The Baltimore Orioles will bring right-handed pitcher Zach Eflin back from the injured list Wednesday to start that night's game against the host Cleveland Guardians.
Orioles vs. Guardians odds, line, prediction, time: 2025 MLB picks, best bets for July 22 by proven model
SportsLine's model simulated Baltimore Orioles vs. Cleveland Guardians 10,000 times and revealed its MLB picks for Tuesday's matchup at Progressive Field in Cleveland
Bowen Island Undercurrent
Cleveland Guardians and Baltimore Orioles meet in game 2 of series
Baltimore Orioles (44-55, fifth in the AL East) vs. Cleveland Guardians (49-50, second in the AL Central) Cleveland; Tuesday, 6:40 p.m. EDT PITCHING PROBABLES: Orioles: Brandon Young (0-4, 7.52 ERA, 1.
Guardians-Orioles, July 21, 2025
Tim Phillis’ photos from Guardians-Orioles on July 21, 2025. Tim Phillis' photos from Guardians-Orioles on July 21, 2025.Tim Phillis' photos from Guardians-Orioles on July 21, 2025.Tim Phillis' photos from Guardians-Orioles on July 21, 2025.Tim Phillis' photos from Guardians-Orioles on July 21, 2025.Tim Phillis' photos from Guardians-Orioles on July 21, 2025.Jose Ramirez swings against the Orioles on July 21. (Tim Phillis - for The News-Herald)T…
Series against Orioles could determine Guardians’ buy or sell deadline strategy
CLEVELAND, Ohio — The Guardians are riding a hot streak at precisely the right moment. Having won eight of their last ten games, they’ve injected life into their season after a 10-game losing streak just as the July 30 trade deadline looms on the horizon. But the front office faces a pivotal question: Is this surge enough to justify adding talent, or should they be looking to deal veterans for future assets?
Associated Press News
Guardians host the Orioles to begin 4-game series
The Cleveland Guardians host the Baltimore Orioles to open a four-game series.
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