Atom-swapping method successfully applied to complex organic structures—new possibilities for drug design

New atom-swapping method applied to complex organic structures

Chemists have developed an efficient skeletal editing method for frequently used heteroaromatic structures. The technique could serve as a means to chemically modify biologically active compounds.

Atom-swapping method successfully applied to complex organic structures—new possibilities for drug design

Skeletal editing is a modern approach to chemical synthesis. By making precise alterations at the atomic level, researchers are able to directly convert existing drug scaffolds into new, biologically relevant compounds.