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AstraZeneca’s Enhertu Slashes Breast Cancer Recurrence Risk in Landmark Trial

Summary by MyChesCo
WILMINGTON, DE — AstraZeneca and Daiichi Sankyo reported breakthrough results from the Phase III DESTINY-Breast05 trial, showing that their drug ENHERTU (fam-trastuzumab deruxtecan-nxki) cut the risk of disease recurrence or death by 53% compared with the current standard therapy, T-DM1, in patients with high-risk HER2-positive early breast cancer following neoadjuvant treatment. The findings, unveiled during the European Society for Medical Onc…
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MyChesCo broke the news in on Tuesday, November 4, 2025.
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