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AstraZeneca to invest $2B in Maryland manufacturing expansion, creating 300 jobs

The $2 billion investment will nearly double AstraZeneca's commercial manufacturing capacity and create 2,600 skilled and construction jobs, strengthening the U.S. medicine supply chain.

  • On Friday, AstraZeneca announced a $2 billion investment to expand manufacturing in Maryland, including Frederick's biologics facility and a new clinical plant in Gaithersburg, supporting 2,600 jobs.
  • Planned expansion will nearly double Frederick facility's commercial capacity and begin rare disease portfolio production; officials said it strengthens the U.S. medicine supply chain and fits AstraZeneca's $50 billion U.S. investment.
  • The company said it is investing about $1.81 billion in capital expenditures, with Frederick creating 200 skilled jobs and 900 construction roles while Gaithersburg adds 100 jobs, retains 400 roles, and supports 1,000 construction jobs.
  • Officials said the investment strengthens the U.S. medicine supply chain, and both facilities are expected to be operational in 2029 while meeting environmental standards using AI, automation and data analytics.
  • `This is the single largest private investment in the state of Maryland in at least the past 10 years`, Gov. Wes Moore said as AstraZeneca's footprint includes over 25,000 U.S. employees supporting more than 100,000 jobs.
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AstraZeneca to Invest $2B in Maryland, expanding manufacturing and creating 2,600 jobs

AstraZeneca, a global, science-based biopharmaceutical company, will invest $2 billion in Maryland to expand manufacturing, according to Governor Wes Moore.

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The Business Journals broke the news in United States on Friday, November 21, 2025.
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