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Treatment Intensification Slows Metastatic Hormone-Sensitive Prostate Cancer

Summary by MedPage Today
(MedPage Today) -- CHICAGO -- Men with metastatic castration-sensitive prostate cancer (mCSPC) and DNA repair alterations had significantly longer progression-free survival (PFS) with a targeted drug plus an androgen receptor pathway inhibitor...

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A new combination of drugs, the enzalutamide androgen inhibitor and the talazoparib PARP inhibitor, has shown a 52% reduction in the risk of progression or death in patients with metastatic prostate cancer with altered DNA repair genes. Thus, it follows from the results of the phase 3 trial named TALAPRO-3, in which Vall d'Hebron has participated the Institute of Oncology (VHIO) and which has been presented at the Congress of the American Societ…

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European Medical Journal broke the news on Saturday, May 30, 2026.
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