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Ancient Immune Protein Could Hold the Key to Better Cancer Immunotherapy

Summary by Sci Tech Daily
A protein known for circulating in the blood to fight infection plays a very different role when produced by cells inside tumors. A protein that emerged long before animals developed circulatory systems may influence whether cancer immunotherapy succeeds. Researchers at Nagoya University in Japan found that complement C3 helps keep immunosuppressive cells out of tumors, [...]

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Researchers at Nagoya University in Japan have discovered that the C3 protein, known for its role in fighting infections, plays a crucial role in the tumor microenvironment, influencing the effectiveness of immunotherapy. Local production of this protein within tumors is fundamental to preventing the entry of immunosuppressive cells, which can improve treatment outcomes. C3 and its function in the tumor microenvironment The C3 protein, which aro…

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Sci Tech Daily broke the news in Encinitas, United States on Saturday, August 1, 2026.
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