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Alzheimer’s Biomarkers Change After Tuberculosis Vaccination
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Alzheimer’s Biomarkers Change After Tuberculosis Vaccination
(MedPage Today) – The bacillus Calmette-Guérin (BCG) vaccine, commonly used against tuberculosis, changed how immune cells behaved and altered markers linked to Alzheimer’s disease in a pilot study involving two open-label trials. In a year-long study, BCG vaccination induced persistent, trained immunity-like changes in cerebrospinal fluid (CSF), including enhanced innate immune responsiveness, reported Steven Arnold, MD, of Massachusetts Genera…
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