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Alpha-Synuclein Initiates Early Gene Expression Shifts in Parkinson’s
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Alpha-Synuclein Initiates Early Gene Expression Shifts in Parkinson’s
In a groundbreaking study set to reshape our understanding of Parkinson’s disease and related synucleinopathies, researchers from Saarland University have unveiled critical insights into how excess alpha-synuclein, a protein closely linked to neurodegenerative disorders, orchestrates profound and region-specific gene expression changes in the brain. Published in the October 20, 2025, issue of Aging-US, this investigation leverages a novel transg…
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