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Machine Learning Model Helps Identify Patients at Risk of Postpartum Depression

  • Researchers led by Dr. Roy Perlis developed a machine-learning model in 2025 to predict postpartum depression risk using data from over 29,000 people in the United States.
  • The model was created because current postpartum depression diagnosis relies mainly on subjective questionnaires and typically occurs weeks after delivery, delaying care.
  • Using electronic health records at delivery, the tool integrates clinical and demographic data to identify individuals at elevated risk, excluding those with recent depression histories.
  • The study found that parents identified as high risk by the model had approximately triple the chance of experiencing postpartum depression, with 30% of them developing the condition within six months after delivery.
  • The model’s early risk identification could enable timely interventions like therapy and stress management, though further validation and clinical integration are ongoing priorities.
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Nature broke the news in United Kingdom on Monday, May 19, 2025.
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