Agouti integrates environmental cues to regulate paternal behaviour

Agouti integrates environmental cues to regulate paternal behaviour

Paternal care is rare among mammals and the neural mechanisms governing its emergence are poorly understood1. We leveraged the natural paternal behaviour of African striped mice (Rhabdomys pumilio)2,3, and integrated brain-wide cFos mapping, single-nucleus RNA sequencing, virally mediated gene perturbation and environmental manipulation to dissect the neural basis of natural variation in male parenting. Here we find that socio-environmental cond…