Sprint or Marathon? Aging Muscle Stem Cells Shift From Rapid Repair to Long-Term Survival

Sprint or marathon? Aging muscle stem cells shift from rapid repair to long-term survival

Aging muscles heal more slowly after injury—a frustrating reality familiar to many older adults. A UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher levels of a protein that slows their ability to activate and repair tissue, but helps the cells survive longer in the harsh environment of aging tissue.

Muscle stem cells build resilience but lose regenerative power with age

Aging muscles heal more slowly after injury — a frustrating reality familiar to many older adults. A new UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher levels of a protein that slows their ability to activate and repair tissue, but helps the cells survive longer in the harsh environment of aging tissue. The findings, published today in the journal Science, suggest that some molecular changes…

Aging Muscle Stem Cells Trade Repair Speed for Survival

Aging muscles heal more slowly after injury - a frustrating reality familiar to many older adults.