After early-life stress, astrocytes can affect behavior

After early-life stress, astrocytes can affect behavior

Astrocytes in the lateral hypothalamus region of the brain, an area involved in the regulation of sleep and wakefulness, play a key role in neuron activity in mice and affect their behavior, Canadian researchers have found.

Astrocyte Disruption Tied to Depression After Childhood Stress

Researchers have shown that astrocytes in the lateral hypothalamus play a pivotal role in how stress shapes behavior, particularly after early-life adversity. In mice, stress led to smaller, less branched astrocytes and abnormal orexin neuron activity, with sex-specific patterns in activity levels.

After early-life stress, astrocytes affect behaviour