Evolutionary Mutation Weakens Human Immune Response to Solid Tumors

Evolutionary mutation weakens human immune response to solid tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

A single genetic mutation may have made humans more vulnerable to cancer than chimpanzees

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates. This insight could lead to more powerful cancer treatments.

A Single Genetic Mutation May Have Made Humans More Vulnerable to Cancer Than Chimpanzees

An evolutionary change in an immune protein, Fas Ligand, makes it vulnerable to inactivation from a tumor-associated enzyme, plasmin. The insight may lead to better cancer treatments.