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A Single Dose of Psilocybin May Produce Lasting Brain Changes, Study Finds

Summary by The Debrief
A new study shows that one psychedelic experience doesn’t just alter how a person feels; it may also change the brain itself. Researchers at UC San Francisco and Imperial College London found that a single 25 mg dose of psilocybin produces signs of likely anatomical changes in the brain that persist for at least a month after the experience. Published in Nature Communications, the study was conducted in healthy adults with no prior psychedelic u…

4 Articles

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A single dose of psilocybine, the psychoactive compound of "magic mushrooms", appears to cause anatomical changes in the brain that may persist up to a month after the experiment, have found American researchers.

·Montreal, Canada
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A single dose of psilocybine, the psychoactive compound of "magic mushrooms", appears to cause anatomical changes in the brain that can last up to a month after the experiment, have found American researchers.

Scientists at the University of California at San Francisco and Imperial College London have found that a single dose of psilocybin — a psychoactive substance from hallucinogenic mushrooms — can temporarily alter brain structure. The effect lasted up to a month.

·Ukraine
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The Debrief broke the news on Thursday, May 14, 2026.
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