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A Novel Immunocompetent Transgenic Mouse Model of DHF Reveals Syk-Mediated Th2-Polarized Cytokine Storm As a Key Driver of Vascular Leakage
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A Novel Immunocompetent Transgenic Mouse Model of DHF Reveals Syk-Mediated Th2-Polarized Cytokine Storm As a Key Driver of Vascular Leakage
Investigators established the first immunocompetent murine model of dengue hemorrhagic fever (DHF) with intact innate/adaptive immunity by generating hTim4-transgenic C57BL/6J mice. [Emerging Microbes & Infections] Full Article
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