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A new CRISPR startup is betting regulators will ease up on gene-editing

Aurora Therapeutics aims to treat an estimated 13,500 U.S. patients with phenylketonuria using a base-editing platform and a new FDA pathway requiring data from few patients.

Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013, calling it the biggest biotech breakthrough of the century. Yet so far, there’s been only one gene-editing drug approved. It’s been used commercially on only about 40 patients, all with sickle-cell disease. It’s becoming clear that the impact of CRISPR isn’t as big as we all hoped. In fact, there’s a pall of discouragement over the entire field—…

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The "CRISPR gene-editing tool" is a crucial foundation for genome-editing technologies in many fields – from biology and medicine to agriculture and industry. A team from the Helmholtz Institute... has shown that the CRISPR-Cas systems that form its basis are even more versatile than previously thought.

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bionity.com broke the news in on Friday, January 9, 2026.
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