US Edition
How an Autism-Linked Mutation Reduces Vasopressin and Alters Social Behavior
Targeting vasopressin receptor AVPR1a restored sociability in male mice with Shank3 mutation without increasing aggression, suggesting potential personalized autism therapies.
5 Articles
5 Articles
How an autism-linked mutation reduces vasopressin and alters social behavior
A team of researchers has identified for the first time the mechanism linking a mutation in the Shank3 gene with alterations in social behavior. Using a mouse model carrying this autism-associated mutation, the study shows that vasopressin, a brain hormone essential for social relationships, is not properly released in the lateral septum.
Autism Gene Found to Alter Brain’s Social Hormone Signals
A new study reveals how a mutation in the Shank3 gene, associated with autism, alters social behavior by disrupting vasopressin release in the brain. In mice, this mutation reduced sociability and defensive aggression by limiting vasopressin reaching the lateral septum.
An international study led by the Institute of Neurosciences of the Spanish National Council for Scientific Research (CSIC) and the Miguel Hernández University (UMH) in Elche has discovered the mechanism that links a genetic mutation linked to autism with alterations in social behavior. The work, published in the journal Nature Communications, is based on a mouse model […] The entry They identify for the first time the relationship between a gen…
RUVID
Salud a DiarioThe Institute of Neurosciences (IN), a mixed center of the Higher Council of Scientific Research (CSIC) and the Miguel Hernández University (UMH) of Elche, leads an international study that identifies for the first time the mechanism that connects a mutation in a gene related to autism with alterations in social behavior. Using a mouse model with a mutation of this gene, the study shows that vasopressin, a brain hormone key in social relations, …
Coverage Details
Bias Distribution
- 100% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
