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New research reveals clues about memory from the brains of 'SuperAgers'
CHICAGO, ILLINOIS, AUG 8 – A 25-year Northwestern study of 290 SuperAgers shows their brains resist or tolerate Alzheimer’s pathology, with 77 brains autopsied revealing key neurobiological traits behind memory resilience.
- Mesulam Center researchers published Thursday a 25-year review, revealing SuperAgers aged 80+ perform as well as much younger adults in memory.
- More than 7 million Americans live with Alzheimer’s, projected to soar to nearly 13 million by 2050, according to the Alzheimer’s Association.
- With advanced imaging, researchers found SuperAgers have three times fewer tau tangles in the hippocampus, a thicker anterior cingulate cortex, and microglia levels matching those of people in their 30s, 40s, and 50s.
- Building on these discoveries, Dr. Sandra Weintraub, Professor at Northwestern University Feinberg School of Medicine, said `This opens the door to new interventions aimed at preserving brain health well into the later decades of life`.
- Today, Gefen said her team’s most exciting findings stem from brains of SuperAgers who have died, involving 101 participants in Mesulam Center research.
21 Articles
21 Articles
SuperAger brains show cognitive decline isn’t inevitable
A donated SuperAger brain. Credit: Shane Collins, Northwestern University Sometimes it can be useful to investigate when things in the brain go right, rather than wrong, to understand human pathologies such as Alzheimer’s and dementia. Researchers at Northwestern University in the US have been studying “SuperAgers” – adults over the age of 80 who have the memory capacity of individuals at least 3 decades younger – for the past 25 years to better…
Superagers' Brains Are Different: Here's How
(MedPage Today) -- Superagers -- a group of adults over age 80 with the memory capacity of much younger people -- maintained good brain morphology, tended to be gregarious, and appeared to be resistant to neurofibrillary degeneration and resilient...
This week in science: Eagles in Japan, the lives of deep-sea animals and 'SuperAgers'
Regina Barber and Rachel Carlson of Short Wave talk about endangered eagles in Japan, the lifestyles of deep-living ocean creatures and the longevity secrets of human 'SuperAgers,' aged 80 and older.
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