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At least 9 dead, 11 injured in UPS plane crash and explosion at Kentucky airport

The fully fueled UPS cargo plane headed to Honolulu crashed causing a large fire; at least 7 fatalities and 11 injuries reported, with the airport shut down and shelter-in-place ordered.

  • On Nov. 4, a UPS cargo plane crashed shortly after takeoff at Louisville Muhammad Ali International Airport around 5:15 p.m., killing at least seven people.
  • The aircraft, an MD-11 bound for Honolulu, was fully fueled for a long-haul flight and carried three crewmembers aboard UPS Flight 2976.
  • A towering plume of smoke was visible for miles and video footage showed a fireball, while over 200 first responders worked for hours to contain the blaze, Louisville Fire Chief Brian O'Neill said.
  • On Nov. 5, Jefferson County Public Schools canceled classes for roughly 93,000 students and more than 17,000 employees and will test air and water quality, while shelter-in-place orders were reduced to a quarter-mile radius.
  • The crash ranks as the deadliest in UPS Airlines history, prompting a major probe by the National Transportation Safety Board and Federal Aviation Administration at UPS Worldport.
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At least seven people were killed and eleven injured following the crash of a UPS cargo plane that crashed on Tuesday afternoon near Muhammad Ali International Airport in Louisville, Kentucky, leaving a trail of fire and destruction, local authorities confirmed.

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USA Today broke the news in United States on Tuesday, November 4, 2025.
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