49ers injury report: George Kittle, Nick Bosa, and Christian McCaffrey cleared to play vs. Rams
San Francisco will have its top playmakers available as the 49ers open the season against the Rams in the NFL’s first regular-season game in Australia.
- On Thursday, the San Francisco 49ers open their 2026 season against the Los Angeles Rams at the Melbourne Cricket Ground in Australia, with stars Nick Bosa, George Kittle, and Christian McCaffrey expected to play.
- Both Bosa and Kittle return from significant injuries sustained in 2025, with Bosa recovering from an ACL tear and Kittle from an Achilles injury; head coach Kyle Shanahan plans to manage their workloads carefully.
- Defensive tackle Alfred Collins is ruled out after sustaining a torn patellar tendon this week, while defensive tackle James Thompson Jr. remains questionable with a hamstring injury.
- Following Thursday's practice, Bosa said he is "100 percent ready to go for the first game," as the team navigates defensive end Sam Okuayinonu's placement on Injured Reserve last week.
- Facing the Rams and MVP quarterback Matthew Stafford, San Francisco relies on McCaffrey, who rushed for 1,202 yards and 10 touchdowns during the 2025 season.
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Rams vs. 49ers injury report: Latest on Myles Garrett, Aaron Donald, George Kittle and more for Week 1
After the 2026 NFL season opened on Wednesday with the Seattle Seahawks defeating the New England Patriots, another mouthwatering matchup awaits on Thursday as the Los Angeles Rams take on the San Fra
49ers Get Good News on $170 Million Star Before Rams Game
The San Francisco 49ers will be nearly at full strength for their season opener against the Los Angeles Rams, and one of the biggest pieces of that puzzle is Nick Bosa. The star defensive end carries no injury designation heading into Thursday’s game in Melbourne, according to Matt Maiocco of NBC Sports Bay Area.Bosa was […]
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