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340B Hit $81 Billion in 2024 (+23%): Why CMS and the IRA Are Poised to Cool the Program’s Runaway Growth

Summary by RetailWit
Whoa. The 340B Drug Pricing Program has once again given new meaning to the word “skyrocketing.” For 2024, discounted purchases under the 340B program reached a record $81.4 billion—an astounding $15.1 billion (+23%) higher than 2023. The gross-to-net difference between list prices and discounted 340B purchases—a proxy for funds available to covered entities—also grew, to $66.4 billion (+$6.0 billion). Hospitals again accounted for 87% of 340B p…
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RetailWit broke the news in on Monday, December 15, 2025.
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