Memory Loss Is Fuelled by Gut Microbes in Ageing Mice
Stanford researchers identified Parabacteroides goldsteinii as a key gut bacterium impairing memory by disrupting vagus nerve signaling in aging mice.
8 Articles
8 Articles
It's often said that memory declines with age. However, not everyone ages equally. Some people maintain sharp cognitive abilities well into their 100s, while others experience memory decline starting in middle age. Recently, the scientific community has shifted its focus from simply attributing age-related forgetfulness to the aging brain, focusing instead on how the brain connects with other organs.
Gut microbes affect cognition during ageing
As mice age, changes in the microorganisms in their guts contribute to cognitive decline by altering signalling between the gut and brain. As mice age, changes in the microorganisms in their guts contribute to cognitive decline by altering signalling between the gut and brain.
Memory loss is fuelled by gut microbes in ageing mice
Edward Chen in Nature: A species of gut bacteria that proliferates as mice get older plays a part in cognitive decline, a study finds1. Researchers determined that the bacterium interferes with signalling along sensory nerves that connect to the brain. Although the experiments were conducted in mice, the gut–brain circuit that the team identified “is likely conserved in humans”, says David Vauzour, a biochemist at the University of East Anglia i…
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