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Memory Loss Is Fuelled by Gut Microbes in Ageing Mice

Stanford researchers identified Parabacteroides goldsteinii as a key gut bacterium impairing memory by disrupting vagus nerve signaling in aging mice.

Summary
If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline. If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.

8 Articles

Lean Right

It's often said that memory declines with age. However, not everyone ages equally. Some people maintain sharp cognitive abilities well into their 100s, while others experience memory decline starting in middle age. Recently, the scientific community has shifted its focus from simply attributing age-related forgetfulness to the aging brain, focusing instead on how the brain connects with other organs.

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Nature broke the news in United Kingdom on Wednesday, March 11, 2026.
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